摘要
目的介绍1例透明带锯齿状伴无间隙卵母细胞的不孕患者成功活产病例。方法对本中心1例透明带锯齿状伴无间隙卵母细胞的不孕患者临床资料和实验室处理进行分析,并对相关文献进行系统性回顾。结果患者冻融周期孕40+4周成功顺产分娩一活女婴。结论透明带锯齿状伴无间隙卵母细胞会影响受精及胚胎发育等,改变受精方式和采用囊胚培养的方式有助于挑选可利用胚胎并获得良好的妊娠结局。
Objective To report a rare case of serrate zona pellucida with interstitial-free oocyte resulting a live baby.Methods The clinical materials and embryo laboratory treatment from one case with morphological abnormality of oocyte zone pellucida was retrospectively analyzed, and associated literatures were reviewed. Results The patient successfully delivered a live female baby at 40+4 weeks of freeze-thaw cycle. Conclusion The serrate zona pellucida with interstitial-free oocyte may affect fertilization and embryo development, change fertilization way and the method of blastocyst culture is helpful to select available embryos and obtain good pregnancy outcome.
作者
史蕾
张铭
王燕
李莉
覃菊玲
马玲
SHI Lei;ZHANG Ming;WANG Yan;LI Li;QIN Juling;MA Ling(Center of Reproductive Medicine,Zhongnan Hospital of Wuhan University,Wuhan,Hubei 430071,China)
出处
《中国优生与遗传杂志》
2021年第11期1610-1613,共4页
Chinese Journal of Birth Health & Heredity
基金
湖北省卫生健康委科研面上项目(WJ2021M162)。
关键词
卵母细胞
锯齿状透明带
受精方式
临床结局
oocyte
serrate zona pellucida
method of fertilization
clinical outcome