2006至2017年本院首次住院肝脏穿刺诊断丙型病毒性肝病患者变化分析

Analysis of changes of patients with hepatitis C virus liver disease diagnosed by liver biopsy for the first time in our hospital from 2006 to 2017

目的分析2006至2017年本院首次住院肝脏穿刺诊断丙型病毒性(HCV)肝病患者变化情况。方法提取2006至2017年本院首次住院肝穿诊断丙型病毒性肝病病案首页信息,对患者性别、年龄、来源地、疾病种类、病理诊断炎症及纤维化等级进行分析。结果首次住院肝脏穿刺诊断丙型病毒性肝病的患者人数逐年上升,2012年后逐年下降。2006至2017年男性例数总体多于女性,两者比较差异有统计学意义(P<0.05)。HCV感染不同阶段中慢性肝炎患者占比最高,但2016年后HCV相关肝癌患者占比逐渐升至最高,差异有统计学意义(P<0.05)。结论2006至2017年本院首次住院肝脏穿刺诊断丙型病毒性肝病患者的年龄、性别、来源地及疾病不同阶段均有明显变化,利于临床医生进一步了解该类疾病的变化,可为今后制订疾病的防控措施和治疗方案提供依据。

Objective To analyze the changes of patients with hepatitis C virus(HCV)liver disease diagnosed by liver biopsy for the first time in our hospital from 2006 to 2017.Methods The first page information of HCV liver disease diagnosed by liver biopsy for the first time in our hospital from 2006 to 2017 was extracted,and the gender,age,source,disease type,pathological diagnosis of inflammation and fibrosis grade were analyzed.Results The number of patients with HCV liver disease diagnosed by liver puncture for the first time increased year by year,and decreased year by year after 2012.From 2006 to 2017,the number of males was generally more than that of females,and the difference was statistically significant(P<0.05).The proportion of patients with chronic hepatitis was the highest in different stages of HCV infection,but the proportion of patients with HCVrelated liver cancer gradually increased to the highest after 2016,and the difference was statistically significant(P<0.05).Conclusion There are significant changes in age,gender,origin and disease stages of patients with HCV liver disease diagnosed by liver puncture for the first time in our hospital from 2006 to 2017,it is helpful for clinicians to further understand the changes of such diseases,and provide a basis for the formulation of disease prevention and control measures and treatment plans in the future.