血清Hcy检测在脑梗死诊断中的应用价值分析

Analysis of the application value of serum Hcy detection in the diagnosis of cerebral infarction

目的:分析血清同型半胱氨酸(Hcy)检测在脑梗死诊断中的应用价值。方法:选择近年来广州中医药大学东莞医院收治的90例脑梗死患者及同期在该医院进行体检的30例健康人作为研究对象。将其中90例脑梗死患者设为观察组,将其中30例健康人设为对照组,并根据观察组患者的年龄将其分为青年组(<45岁)、中年组(45~60岁)与老年组(>60岁)。检测并比较各组研究对象血清Hcy的水平,统计用血清Hcy检测诊断观察组患者病情的效能。结果:观察组患者血清Hcy的水平和血清Hcy水平异常的检出率均高于对照组健康人,P<0.05。老年组患者血清Hcy的水平高于青年组患者,P<0.05。中年组患者、老年组患者血清Hcy水平异常的检出率均高于青年组患者,P<0.05。老年组患者血清Hcy水平异常的检出率高于中年组患者,P<0.05。用血清Hcy检测诊断观察组患者病情的特异度为91.67%、灵敏度为89.74%、准确率为90.00%。结论:用血清Hcy检测诊断脑梗死的价值较高。

Objective:To analyze the application value of serum homocysteine(Hcy)in the diagnosis of cerebral infarction.Methods:A total of 90 patients with cerebral infarction admitted to Dongguan Hospital of Guangzhou University of Chinese Medicine in recent years and 30 healthy people who underwent physical examination in the same period were selected as subjects.Ninety patients with cerebral infarction were set as the observation group,and 30 healthy people were set as the control group.According to the age of patients in the observation group,they were divided into young group(<45 years old),middle-aged group(45-60 years old)and old group(>60 years old).Serum Hcy levels of subjects in each group were detected and compared,and the efficacy of serum Hcy detection in diagnosing the disease of patients in the observation group was analyzed.Results:The serum Hcy level and abnormal detection rate of serum Hcy level in observation group were higher than those in control group,P<0.05.The level of serum Hcy in the elderly group was higher than that in the young group,P<0.05.The detection rate of abnormal serum Hcy level in middle-aged group and elderly group was higher than that in young group,P<0.05.The detection rate of abnormal serum Hcy level in the elderly group was higher than that in the middle-aged group,P<0.05.The specificity,sensitivity and accuracy of serum Hcy were 91.67%,89.74%and 90.00%in the observation group.Conclusion:Serum Hcy is of high value in diagnosis of cerebral infarction.