不同液体治疗方案对腹部大手术患者急性肾损伤发生率影响的研究进展

The research advances of the effect of different fluid treatments on acute kidney injury in patients undergoing major abdominal surgery

腹部大手术患者术后急性肾损伤(acute kidney injury,AKI)发生率较高,严重影响患者预后。围手术期容量灌注水平是术后AKI发生的重要影响因素之一,不同的容量治疗方案与其密切相关,但目前术中液体管理方案仍存在争议。文章回顾了近年来有关液体管理方案的相关研究及各项Meta分析结果,探讨优化的术中液体管理策略,以期为预防或减少术后AKI的发生、改善患者预后提供一定的理论基础。

Acute kidney injury(AKI)after major abdominal surgery is highly prevalent and seriously influence patients'prog‑nosis.Fluid therapy is one of the important factors influencing the occurrence of the postoperative AKI while the intraoperative fluid management scheme is still controversial.Having reviewed the recent research on fluid management programs as well as relevant metaanalysis,this study tries to explore the optimal intraoperative fluid management strategy,to prevent or reduce the incidence of postoperative AKI and improve patient prognosis.