腹型肥胖与2型糖尿病中医病理因素的关联性研究

Correlational study of TCM pathogenic factors of type 2 diabetes and abdominal obesity

目的:探索腹型肥胖与2型糖尿病中医病理因素的关联性。方法:选取我院297例2型糖尿病患者,分析腹型肥胖与2型糖尿病中医病理因素的相关性。结果:(1)两组证素在阴虚、湿、痰上差异有统计学意义;(2)在相关分析中,男性腹型肥胖腰围与痰极其显著正相关,而女性腹型肥胖腰围与阴虚显著负相关,与痰极其显著正相关,与湿极其显著正相关。在多重线性回归分析中,男性腹型肥胖腰围与证素无关,而女性腰围与痰偏回归系数为正,与气滞偏回归系数为负。结论:(1)2型糖尿病腹型肥胖组湿、痰证素明显高于正常组,而阴虚高于正常组;(2)随着腰围的增粗,男、女痰证素成立性可能性大,女性湿证素成立性也增大,而女性阴虚证素成立性下降;(3)痰是女性腹型肥胖与2型糖尿病关联的重要中医病理因素。

Objective: To explore the correlation between abdominal obesity and TCM pathogenic factors of type 2 diabetes. Methods: We selected 297 type 2 diabetes patients in our hospital and analyzed the correlation between abdominal obesity and TCM pathogenic factors of type 2 diabetes. Results:(1)There were statistically significant differences between the two groups in syndrome factors including yin deficiency, dampness and sputum;(2)Correlation analysis showed that the waist circumference of abdominal obesity male was signifi-cantly positively correlated with sputum, while the waist circumference of abdominal obesity female was significantly negatively correlated with yin deficiency, significantly positively correlated with sputum and dampness. Multiple linear regression analysis showed that the waist circumference of abdominal obesity male was independent of syndromes, while the partial regression coefficient of the waist circumference of female and sputum was positive and the partial regression coefficient of the waist circumference of female and qi stagnation was nega-tive. Conclusion:(1)Dampness and sputum in type 2 diabetes abdominal obesity group are significantly higher than those in normal group, while yin deficiency is significantly higher than that in normal group.(2)With the increase of waist circumference, sputum is more likely to appear both in male and female, and the occurrence rate of dampness increases in female too, while yin deficiency decreases.(3)Sputum is an important TCM pathogenic factor associated with abdominal obesity and type 2 diabetes in women.