温肾健脾定脊汤对肾虚督亏、脾病湿困型强直性脊柱炎的临床疗效

Clinical efficacy of the Wenshen Jianpi Dingji decoction on ankylosing spondylitis of syndrome of Du insufficiency and kidney deficiency,dampness stagnancy due to splenopathy

目的:探究肾虚督亏、脾病湿困型强直性脊柱炎(Ankylosing Spondylitis,AS)采用温肾健脾定脊汤治疗的临床疗效。方法:将2016年2月-2020年9月在广州市增城区中医医院接受治疗的53例肾虚督亏、脾病湿困型AS患者视为研究对象,以随机数字表法分为两组,甲组采用西药治疗,乙组在甲组基础上联合温肾健脾定脊汤治疗,对比两组临床疗效、治疗前后巴氏AS功能指数(Bath AS Metrology Index,BASMI)、巴氏AS活动指数(Bath AS Activity Index,BASDAI)、视觉模拟评分法(Visual Analogue Scale,VAS)评分、C反应蛋白(C-reactive Protein,CRP)、红细胞沉降率(Erythrocyte Sedimentation Rate,ESR)、中医证候积分变化情况。结果:与甲组比较,乙组治疗总有效率更高(P<0.05);与甲组比较,乙组治疗后BASMI、BASDAI、VAS评分均更低(P<0.05);与甲组比较,乙组治疗后CRP、ESR均更低(P<0.05);与甲组比较,乙组治疗后各项中医证候积分更低(P<0.05)。结论:肾虚督亏、脾病湿困型AS采用温肾健脾定脊汤治疗的临床疗效理想,利于促进病情恢复,减轻患者疼痛。

Objective:To explore the clinical efficacy of the Wenshen Jianpi Dingji decoction(温肾健脾定脊汤)on ankylosing spondylitis of syndrome of Du meridian(督)insufficiency and kidney deficiency,dampness stagnancy due to splenopathy.Methods:From February 2016 to September 2020,53 patients were divided into two groups.The group A was treated with Western medicine,and the group B was treated with the Wenshen Jianpi Dingji decoction on the basis of the group A.Rgesults:After treatment,compared with group A,the total efficiency in group B was higher(P<0.05);BASMI,BASDAI,VAS,CRP,ESR,and TCM syndrome scores in group B were all lower(P<0.05).Conclusion:The Wenshen Jianpi Dingji decoction on ankylosing spondylitis of syndrome of Du meridian insufficiency and kidney deficiency,dampness stagnancy due to splenopathy gains a good clinical effect,and relieves pain.