厚朴三物汤与厚朴七物汤在“腹满”病中的药理研究

A pharmacological study on the Houpo Sanwu decoction and the Houpo Qiwu decoction in treating abdominal fullness diseases

《金匮要略》针对不同的"腹满"病证分别提出了厚朴三物汤和厚朴七物汤。二者的方剂组成、制备、服用策略都有所不同。对两种方剂进行比较研究,不仅有助于在临床诊断中辨析具体病证,以便正确用药,也可以加深研究者对药物具体成分和功效的认识,对于整理方剂、开发新方有积极的促进作用。文章通过对《金匮要略》中厚朴三物汤和厚朴七物汤的组成成分、制备工艺和两种方剂治疗"腹满"病证的比较研究,提出了厚朴三物汤经破气消积治疗阳明病,厚朴七物汤由温阳补虚来通利腑气的观点,两种方剂虽然相似,但其药理却有所不同。

In Jin’gui Yaolue(《金匮要略》),the Houpo Sanwu decoction(厚朴三物汤)and the Houpo Qiwu decoction(厚朴七物汤)was given for different abdominal fullness diseases.The composition,preparation method and taking strategy of the two decoctions were different.A comparative study on the two prescriptions is not only helpful to identify specific symptoms in clinical diagnosis for correct medication,but also can deepen the researchers’understanding on the specific ingredients and efficacy of the related medicines,and will paly a positive role in integrating prescriptions and developing new prescriptions.In this paper,from the aspects of prescription composition,preparation technology and clinical effects on abdominal fullness diseases,the Houpo Sanwu decoction and the Houpo Qiwu decoction for abdominal fullness diseases in Jin’gui Yaolue were comparatively studied.It is proposed that the Houpo Sanwu decoction treats Yangming(阳明)diseases by dissolving Qi(气)and eliminating accumulation,and the Houpo Qiwu decoction promotes the circulation of Qi of internal organs by warming Yang(阳).Although the two prescriptions are similar,their pharmacology is different.