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非自杀性自伤行为的关键生物基础 被引量:8

The neurobiological basis of non-suicidal self-injury
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摘要 非自杀性自伤行为(non-suicidal self-injury,NSSI)越来越多见,严重影响着患者,尤其是青少年的心理健康,冲动特质、疼痛加工、奖赏环路、内源性阿片系统等在其生物基础方面扮演了重要的角色。本文通过梳理上述4个方面与NSSI有关的研究证据和神经机制,初步阐述NSSI可能的关键生物基础。 Non-suicidal self-injury(NSSI)is becoming increasingly common.NSSI is typically associated with emotional and psychiatric distress and mainly seriously affects mental health in adolescents.Trait impulsivity,reward circuitry,and the endogenous opioid system are all playing an essential role in the neurobiological mechanism.This review conceptualizes the neurobiology of NSSI based upon the new research evidence.
作者 张丽萍 王纯 杭亚明 张聪捷 张宁 Zhang Liping;Wang Chun;Hang Yaming;Zhang Congjie;Zhang Ning(Nanjing Brain Hospital Affiliated to Nanjing Medical University,Nanjing 210029,China)
出处 《中华精神科杂志》 CAS CSCD 北大核心 2022年第2期150-153,共4页 Chinese Journal of Psychiatry
基金 江苏省重点研发计划(社会发展)项目(BE2019609)。
关键词 冲动行为 非自杀性自伤行为 疼痛加工 奖赏环路 内源性阿片系统 Impulsive behavior Non-suicidal self-injury Pain processing Reward circuitry Endogenous opioid system
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