摘要
An iron-catalyzed coupling reaction of difluoroenol silyl ethers and cyclobutanone oxime esters is described. This protocol provides a convenient access to various previously unknown and potentially useful gem-difluoromethylenated ketonitriles inmoderate to good yields. The transformations of resulting products to other fluorinecontaining products is also documented.
基金
National Natural Science Foundation of China (Nos.21421002,21991211)
the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB20000000)。
