舒芬太尼复合丙泊酚、咪达唑仑联合局麻用于儿童包皮环切的效果

Effect of Sufentanil Combined With Propofol,Midazolam and Local Anesthesia on Circumcision in Children

目的探讨儿童包皮环切术时应用舒芬太尼复合丙泊酚、咪达唑仑和局部麻醉的效果。方法选取接受包皮环切术治疗的患儿68例,按照随机数字表法,分为对照组与观察组,各34例。对照组接受舒芬太尼、咪达唑仑、丙泊酚和苯磺顺阿曲库铵行气管插管全身麻醉,观察组接受舒芬太尼、咪达唑仑、丙泊酚进行静脉麻醉,同时采用2%利多卡因实施局部麻醉,比较两组术中心率(heart rate,HR)、收缩压(systolic blood pressure,SBP)、麻醉苏醒时间、苏醒后镇静评分、苏醒后疼痛评分与术后12 h镇痛治疗需求率。结果两组丙泊酚静脉推注完成后、缝线环扎包皮时与术毕时的HR与SBP差异无统计学意义(P>0.05);观察组苏醒后疼痛评分低于对照组,麻醉苏醒时间短于对照组,差异有统计学意义(P<0.05);两组术后12 h镇痛治疗需求率、苏醒后镇静评分差异无统计学意义(P>0.05)。结论儿童包皮环切术时应用舒芬、复合丙泊酚咪达唑仑和局部麻醉药的麻醉效果确切,可减轻患儿苏醒后疼痛情况。

Objective To investigate the effect of sufentanil combined with propofol,midazolam,local anesthetics in circumcision of children.Methods A total of 68 children who received circumcision were selected and divided into the control group and the observation group according to the random number table method,with 34 cases in each group.The control group received sufentanil,midazolam,propofol and cisatracurium besylate for general anesthesia with endotracheal intubation,while the observation group received sufentanil,midazolam and propofol for intravenous anesthesia.At the same time,2%lidocaine was used to perform local anesthesia,and the operation heart rate(HR),systolic blood pressure(SBP),anesthesia recovery time,sedation score after recovery,pain score after recovery and postoperative analgesia treatment requirements were compared between the two groups rate.Results There were no significant differences in HR and SBP between the two groups after intravenous propofol injection,at the time of suture ring circumcision and after operation(P>0.05).The pain score after awakening in the observation group was lower than that in the control group,and the time of anesthesia awakening in the observation group was shorter than that in the control group,with statistical significance(P<0.05).There was no significant difference in 12 h postoperative analgesia treatment demand rate and post-awakening sedation score between the two groups(P>0.05).Conclusion The anesthesia effect of sufentanil combined with propofol,midazolam and local anesthetics during circumcision of children is definite and can relieve the pain after awakening.