左西替利嗪、孟鲁司特联合卡介菌素对慢性荨麻疹的治疗效果分析

Analysis of the Therapeutic Effect of Levocetirizine,Montelukast combined with BCG on Chronic Urticaria

目的研究左西替利嗪、孟鲁司特联合卡介菌素治疗慢性荨麻疹的效果。方法选取山东第一医科大学附属肥城医院2019年2月~2020年11月收治的慢性荨麻疹患者78例,按随机数表法分为对照组和观察组,每组39例。对照组采用卡介菌素联合孟鲁司特治疗,观察组采用左西替利嗪、孟鲁司特联合卡介菌素治疗。比较两组患者生活质量评分、治疗效果、临床症状消退时间。结果治疗后,观察组患者临床症状消退时间显著短于对照组,差异有统计学意义(P<0.05)。治疗后,观察组患者治疗效果显著高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组患者生活质量评分显著高于对照组,差异有统计学意义(P<0.05)。结论左西替利嗪、孟鲁司特联合卡介菌素治疗慢性荨麻疹,能够缩短患者临床症状消退时间,提升患者治疗效果,同时提升患者生活质量,能够给临床治疗慢性荨麻疹方面提供更多的参照,并可在临床应用。

Objective To study the the therapeutic effect of levocetirizine,montelukast combined with BCG Bacillus Calmette-Guerin on chronic urticaria patients.Methods A total of 78 patients with chronic urticaria admitted to Feicheng Hospital Affi liated to Shandong First Medical University from February 2019 to November 2020 were selected.They were included and randomly divided into the observation group and the control group.Among them,39 patients in the observation group received the therapy proctocol of levocetirizine,montelukast combined with BCG,while 39 patients in the control group received Bacillus Calmette-Guerin combined with montelukast.Quality of life score,treatment effi cacy and clinical symptom subsidence time were administated between two groups.Results After treatment,the clinical symptom subsidence time in the observation group was significantly shorter than that in the control group(P<0.05).After treatment,the total efficiency of the observation group was signifi cantly higher than that of the control group(P<0.05).After treatment,the quality of life score of the observation group was signifi cantly higher than that of the control group(P<0.05).Conclusion The therapy protocol of levocetirizine,montelukast combined with BCG in chronic urticaria could signifi catly improve the clinical symptom subsidence time,improve the therapeutic eff ect and increase the quality of life score.