胰腺癌患者失志现状及影响因素研究

Status and influencing factors of demoralisation syndrome in patients with pancreatic cancer

目的了解胰腺癌患者失志综合征现状及影响因素,为制定干预措施提供理论依据。方法采用便利抽样法选取2019年1月—2021年6月温州医科大学附属第二医院收治的162例胰腺癌患者为研究对象。采用一般资料调查问卷、失志量表、领悟社会支持量表、自我感受负担量表进行问卷调查。结果胰腺癌患者失志量表得分为(35.45±11.93)分,领悟社会支持量表得分为(55.64±7.04)分,自我感受负担量表得分为(34.09±8.53)分;不同年龄、性别、学历、婚姻状况、家庭人均月收入、疾病分期、治疗方式的胰腺癌患者失志得分差异有统计学意义(均P<0.05);Pearson相关分析结果显示,胰腺癌患者领悟社会支持总分及各维度得分均与失志得分呈负相关关系(均P<0.01),自我感受负担总分及各维度得分均与失志得分呈正相关关系(均P<0.01);多元线性回归分析结果显示,学历、疾病分期、自我感受负担、领悟社会支持是胰腺癌患者失志综合征的主要影响因素(均P<0.05),可解释总变异的42.1%。结论胰腺癌患者失志综合征程度较高,应根据患者的学历、疾病分期、自我感受负担、领悟社会支持情况采取针对性的干预措施,缓解患者的失志综合征,提高胰腺癌患者的生活质量。

Objective To understand the current situation and influencing factors of demoralisation syndrome in pancreatic cancer patients,and to provide theoretical basis for the formulation of intervention measures.Methods A total of 162 patients with pancreatic cancer admitted to the Second Affiliated Hospital of Wenzhou Medical University from January 2019 to June 2021 were selected as the research objects by convenience sampling method.The general information questionnaire,Demoralization Scale,Perceived Social Support Scale and Self-Perceived Burden Scale were used to conduct the questionnaire survey.Results Patients with pancreatic cancer scored(35.45±11.93)points on the demoralization scale,(55.64±7.04)points on the perceived social support scale and(34.09±8.53)points on the self-perceived burden scale.There were significant differences in the demoralisation scores amongst pancreatic cancer patients with different age,gender,educational background,marital status,per capita monthly family income,disease stage and treatment methods(all P<0.05).The results of Pearson correlation analysis showed that the total score of perceptive social support and the scores of all dimensions were negatively correlated with the scores of demoralisation syndrome(all P<0.01),and the total score of self-perceived burden and the scores of all dimensions were positively correlated with the scores of demoralisation syndrome(all P<0.01).The results of multiple linear regression analysis showed that education background,disease stage,self-perceived burden and perceived social support were the main influencing factors of demoralisation syndrome(all P<0.05),which could explain 42.1%of the total variation.Conclusion Patients with pancreatic cancer have a high level of demoralisation syndrome,and targeted intervention measures should be taken according to patients’educational background,disease stage,self-perceived burden and understanding of social support,so as to alleviate the demoralisation syndrome and improve the quality of life of patients with pancreatic cancer.