完整肠系膜切除术治疗结肠癌47例效果观察

Complete Mesocolic Excision in the Treatment of Colonic Cancer:Effect Observation on 47 Cases

目的:观察完整肠系膜切除术(CME)治疗结肠癌的效果。方法:将结肠癌患者94例随机分为对照组和观察组,每组47例。对照组患者采用传统结肠癌根治术治疗,观察组患者采用CME治疗,对2组患者手术相关指标、手术前后炎症因子水平以及术后并发症发生情况进行比较。结果:观察组患者术中出血量少于对照组,手术时间、肛门排气时间、引流管拔除时间以及住院时间均短于对照组(P <0.05);术前2组患者C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平比较差异无统计学意义(P>0.05),术后2组患者炎症因子水平均有所升高,但观察组患者明显低于对照组(P<0.05);观察组患者术后并发症发生率明显低于对照组(P <0.05)。结论:CME治疗结肠癌对患者创伤小、术后恢复快,可明显降低术后并发症发生率。

Objective To observe the effect of complete mesocolic excision(CME)in the treatment of colonic cancer. Methods Randomly divided 94 patients with colonic cancer into control group(47 cases,received routine radical procedure)and observation group(47 cases,CME for colonic cancer);then,both groups’ patients’ operating norms,the inflammatory factors’ levels before and after surgery,and the incidence status on postoperative complication were compared. Results In preoperative levers of inflammatory factors(CRP,IL-6 and TNF-α)there was no statistical difference between the two groups(P >0.05);but,in intraoperative bleeding volume;in the time for operating,for flatus from anus,for drainage tube removed,and for hospitalization;in postoperative levels of inflammatory factors(CRP,IL-6 and TNF-α);and in postoperative incidence of complication,observation group was respectively less;shorter;lower(though both groups’ one were all some increased);and lower than control group(all,P <0.05). Conclusion CME for treating colonic cancer has such merits as less trauma,fastly postoperative recovery,and significantly reducing postoperative complication.