银川市12~17岁儿童青少年肌肉质量指数和心血管危险因素聚集的关系

Relationship between the muscle mass index and the aggregation of cardiovascular risk factors in children and adolescents aged 12-17 years in Yinchuan City

目的探索儿童青少年肌肉质量指数(muscle mass index,MMI)与心血管危险因素(cardiovascular risk factors,CVRFs)聚集的关系,为儿童青少年心血管疾病的防治提供科学依据。方法采用现况研究设计,以整群随机抽样的方法抽取银川市12~17岁1622名儿童青少年,运用问卷调查、体格检查、体成分测定和实验室指标检测进行调查分析。结果未调整其他变量时,MMI与心血管危险因素聚集呈正相关(P值均<0.01),调整年龄、性别和体质量指数(BMI)后,MMI与CVRFs≥1呈负相关(OR=0.74,95%CI=0.62~0.89)。总人群中,相比于MMI不足,MMI良好及充足与CVRFs≥1的发生风险呈负相关(OR=0.60,95%CI=0.46~0.79;OR=0.56,95%CI=0.37~0.85),与CVRFs≥2的发生风险呈负相关(OR=0.54,95%CI=0.37~0.79;OR=0.51,95%CI=0.30~0.87),男生中也有相似的结果(P值均<0.05)。结论相同BMI水平下,肌肉质量指数是儿童青少年心血管危险因素聚集的保护因素。应重视儿童青少年体育锻炼,保持最佳肌肉质量和体重。

Objective To explore the relationship between the muscle mass index(MMI)and the aggregation of cardiovascular risk factors(CVRFs)in children and adolescents,and to provide a scientific basis for the prevention and treatment of cardiovascular diseases in children and adolescents.Methods The current situation study design was adopted,and 1622 children and adolescents aged 12-17 years old in Yinchuan City were selected by a cluster random sampling method.All subjects were subjected to questionnaire survey,physical examination,body composition determination and laboratory index testing.Results When other variables were not adjusted,MMI was a risk factor for the aggregation of cardiovascular risk factors(P<0.01).After adjusting for age,gender and BMI,MMI became a protective factor for CVRFs≥1(OR=0.74,95%CI=0.62-0.89),compared with insufficient MMI,the risk of developing CVRFs≥1 with good MMI and sufficient MMI was 0.60(95%CI=0.46-0.79),0.56(95%CI=0.37-0.85)times.The risk of CVRFs≥2 was 0.54(95%CI=0.37-0.79),0.51(95%CI=0.30-0.87)times,and similar results were found in boys(P<0.05).Conclusion Under the same BMI level,muscle mass index is a protective factor for cardiovascular risk factor aggregation in children and adolescents.Physical exercise of children and adolescents should be emphasized to maintain the best muscle mass and weight.