身痛逐瘀贴辅助治疗瘀血型膝骨关节炎患者的效果

Effect of Shentong Zhuyu Paste in the auxiliary treatment of patients with blood stasis knee osteoarthritis

目的研究身痛逐瘀贴辅助治疗瘀血型膝骨关节炎(KOA)患者的临床效果。方法将湖南中医药大学第一附属医院门诊部2020年6月至2021年3月接诊的50名瘀血型膝骨关节炎患者,采用随机数字表法分为对照组和治疗组,每组各25例。连续治疗14 d。对照组采用常规疗法,治疗组在对照组的基础上再配合膏贴外用。比较两组治疗后临床疗效,治疗前后凝血功能、KOA中医评分、视觉模拟评分法(VAS)及西安大略和麦克马斯特大学指数(WOMAC)。结果治疗组临床疗效优于对照组,差异有统计学意义(P<0.05)。治疗前后,两组凝血酶原时间、活化部分凝血活酶时间、凝血酶时间和D-二聚体组内及组间比较,差异无统计学意义(P>0.05)。治疗前两组KOA中医评分、VAS评分及WOMAC指数比较,差异无统计学意义(P>0.05);治疗后两组KOA中医评分、VAS评分及WOMAC指数均低于治疗前,且治疗组低于对照组,差异有统计学意义(P<0.05)。结论身痛逐瘀贴辅助治疗瘀血型膝骨关节炎临床效果值得肯定,该方案具有明显的缓解疼痛和改善关节运动功能的作用。

Objective To study the effect of Shentong Zhuyu Paste in the auxiliary treatment of patients with blood stasis knee osteoarthritis(KOA).Methods A total of 50 patients with blood stasis knee osteoarthritis treated in the Department of Outpatient,the First Affiliated Hospital of Hunan University of Chinese Medicine from June 2020 to March 2021 were divided into control group and treatment group by random number table method,with 25 cases in each group.The treatment lasted for 14 days.The control group was treated with conventional therapy,and the treatment group was combined with plaster for external application on the basis of the control group.Clinical efficacy,coagulation function,KOA Chinese medicine score,visual analog scale(VAS)and Western Ontario and mcMaster Universities(WOMAC)index were compared between the two groups.Results The clinical efficacy of the treatment group was better than that of the control group,and the difference was statistically significant(P<0.05).Before ard after treatment,there were no significant differences in prothrombin time,activated partial thromboplastin time,thrombin time and D-Dimer of within and between groups(P>0.05).Before treatment,there were no significant differences in KOA scores,VAS scores and WOMAC index between the two groups(P>0.05).After treatment,KOA Chinese medicine score,VAS score and WOMAC index in two groups were lower than before,and the treatment group was lower than the control group,the differences were statistically significant(P<0.05).Conclusion The clinical effect of Shentong Zhuyu Paste in the auxiliary treatment of blood stasis KOA is worthy of recognition.The treatment has obvious effects of relieving pain and improving joint movement function.