名老中医治疗病毒性心肌炎用药规律的分析

Analysis of medication rules of famous veteran traditional Chinese medicine doctor in the treatment of viral myocarditis

目的针对名老中医治疗病毒性心肌炎医案及中国知网文献进行数据统计及分析,挖掘名老中医治疗病毒性心肌炎的用药规律。方法收集检索时限为建库至2021年2月的名老中医医案著作及中国知网文献中诊断为病毒性心肌炎的医案,经筛选后录入中医传承辅助平台V2.5中,对症状、证候、治则治法、组方规律等进行数据统计,分析患者证候及名老中医用药规律。结果总计纳入医案86例,处方共95首。最常见的证候为气阴两虚证,主要症状为心悸,单味用药频次最多为甘草,四气以寒、温为主,五味以甘、苦为主,归经以心、肺经为主,其中关联规则分析置信度最高的为丹参、五味子→麦冬,新方聚类分析得出8首新处方。结论结合数据分析发现病毒性心肌炎的证型主要为气阴两虚证,名老中医在治疗该病时多将“补”与“清”并用,以益气阴、清热毒为主,化血瘀、安神志、复心脉为辅。

Objective To make data statistics and analysis on the medical records of famous veteran traditional Chinese medicine doctor in treating viral myocarditis and the literatures of CNKI,and to explore the medication rule of famous veteran traditional Chinese medicine doctor in treating viral myocarditis.Methods Medical cases diagnosed with viral myocarditis from famous old TCM medical case books and CNKI literatures were collected and searched from the establishment of database to February 2021,and entered into the traditional Chinese medicine inheritance support platform V2.5,and the data were statistically for symptoms,syndromes,treatment rules and methods,and prescription patterns,etc,the patient’s syndromes and the medication pattern of the famous veteran traditional Chinese medicine doctor were analyzed.Results A total of 86 cases and 95 prescriptions were included.The most common syndrome was the syndrome of deficiency of both qi and yin,the main symptom was palpitations,the most frequent used in a single herb was Radix Glycyrrhizae,and the four nature of drugs were mainly cold and sweet,and the five flavours were mainly sweet and bitter,and the main channels were the heart and lung meridians,and the highest confidence level of the association rule analysis was Radix Salviae Miltiorrhizae,Fructus Schisandrae Chinensis→Radix Ophiopogonis,and the new formula clustering analysis yielded had eight new prescriptions.Conclusion The main type of syndrome of viral myocarditis is the syndrome of deficiency of both qi and yin,in the treatment of this disease,famous veteran traditional Chinese medicine doctors mostly combine“tonifying”and“clearing”,the mainly treatment is supplementing qi and yin,cleaning heat and poison,and the secondary treatment is resolving blood stasis,calming mind and restoring heart pulse.