北京东南部地区成人社区获得性肺炎620例病原学分析

Etiological analysis of 620 adult patients with community acquired pneumonia in southeast of Beijing

目的了解北京东南部地区成人社区获得性肺炎(CAP)的病原学分布特点,为CAP经验性治疗提供依据。方法回顾性分析2016年10月1日至2020年4月30日北京市垂杨柳医院620例CAP患者的病原学分布特点。结果非典型病原体阳性率为40.8%,肺炎支原体占39.4%;细菌检测阳性率为56.8%,肺炎链球菌占35.8%,流感嗜血杆菌占19.0%;病毒检测阳性率为19.7%,甲型流感占5.6%,副流感占5.6%。混合感染率为43.5%,肺炎链球菌合并肺炎支原体最常见。结论肺炎支原体为北京东南部地区成人CAP的首位病原体,肺炎链球菌、流感嗜血杆菌次之,甲型流感病毒及副流感病毒是最常见的病毒病原。且本地区CAP混合感染率高。本研究初步揭示了该地区成人CAP的病原学分布特点,为经验性治疗提供病原学依据。

Objective To investigate the etiological distribution of adult community-acquired pneumonia(CAP)in southeast of Beijing,and to provide evidence for the empirical treatment of CAP.Methods The etiological distribution of 620 CAP patients in Beijing Chuiyangliu Hospital from October 1,2016 to April 30,2020 was analyzed retrospectively.Results The positive rate of atypical pathogens was 40.8%,Mycoplasma pneumoniae was 39.4%;bacteria was 56.8%,Streptococcus pneumoniae was 35.8%,Haemophilus influenzae was 19.0%;the positive rate of virus was 19.7%,influenza A was 5.6%,parainfluenza virus was 5.6%.The positive rate of mixed infection was 43.5%,Streptococcus pneumoniae combined with mycoplasma pneumoniae infection is the most common.Conclusion Mycoplasma pneumoniae is the first pathogen of adult CAP in southeast of Beijing,followed by Streptococcus pneumoniae and Haemophilus influenzae.Influenza A virus and parainfluenza virus are the most common viral pathogens.The mixed infection rate of CAP was high in this area.This study initially revealed the characteristics of aetiological distribution of CAP in adults in the region,and provided etiological evidence for empiric therapy.