龙骨牡蛎粉联合康惠尔泡沫敷料治疗失禁相关性皮炎的效果

Effect of Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of incontinence-related dermatitis

目的探讨龙骨牡蛎粉联合康惠尔泡沫敷料治疗失禁相关性皮炎(IAD)的效果。方法选取2019年2月至2021年4月江苏省如皋市中医院重症监护室收治的106例IAD患者,根据随机数字表法将其分为对照组和研究组,各53例。两组患者均给予常规治疗措施,对照组另给予康惠尔泡沫敷料治疗,研究组在对照组的基础上另给予龙骨牡蛎粉治疗,两组均持续治疗7 d。比较两组治疗前后临床症状评分,观察两组临床疗效、皮肤愈合时间、不良反应及复发情况。结果治疗后,两组临床症状评分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。研究组Ⅱ、Ⅲ级患者皮肤愈合时间均短于对照组,差异有统计学意义(P<0.05)。两组总不良反应发生率、复发率比较,差异无统计学意义(P>0.05)。结论龙骨牡蛎粉联合康惠尔泡沫敷料治疗IAD可改善患者临床症状,增强临床疗效,加快皮肤愈合,且安全性良好。

Objective To explore the effect of Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of incontinence-related dermatitis(IAD).Methods One hundred and six patients with IAD admitted to Intensive Care Unit of Rugao Hospital of Traditional Chinese Medicine in Jiangsu Province from February 2019 to April 2021 were selected and divided into control group and study group according to random number table method,with 53 cases in each group.Both groups were given routine treatment,control group was treated with Kanghuier foam dressing,study group was treated with Longgu Muli Powder on the basis of control group.Both groups were treated for seven days.Clinical symptom scores of two groups were compared before and after treatment.Clinical efficacy,skin healing time,adverse reactions and recurrence were compared between two groups.Results After treatment,clinical symptom scores of two groups were lower than those before treatment,and study group was lower than control group,the differences were statistically significant(P<0.05).Clinical effect of study group was better than that of control group,the difference was statistically significant(P<0.05).Skin healing time of grade Ⅱ and Ⅲ patients in study group were shorter than those in control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of total adverse reactions and recurrence between two groups(P>0.05).Conclusion Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of IAD can improve clinical symptoms of patients,enhance clinical efficacy,accelerate skin healing,with good safety.