基于“瘀去、新生、骨合”理论从细胞层面探讨祛瘀、活血及补肾中药治疗股骨头坏死的作用机制

Investigation on mechanism of action of stasis-removing, blood-activating and kidney-tonifying TCMs in treatment ofosteonecrosis of the femoral head from cellular level based on the theory of stasis-blood-removing, new-blood-regeneration and new-bone-growth

股骨头坏死(osteonecrosis of femoral head,ONFH)是好发于中青年的骨科难治性疾病。中医药为ONFH的保髋治疗提供了许多新的思路,逐渐受到医学界的重视。“瘀去、新生、骨合”理论是中医学关于骨修复的关键理论,也是中医治疗ONFH的理论依据和指导思想,祛瘀、活血及补肾中药为基于这一理论治疗ONFH的常用中药。本文基于“瘀去、新生、骨合”理论,从细胞层面探讨了祛瘀、活血及补肾中药治疗ONFH的作用机制。