生脉散合当归补血汤治疗感染后咳嗽30例

Shengmai Powder Combined with Danggui Buxue Decoction in the Treatment of 30 cases of Cough after Infection

目的 观察生脉散合当归补血汤加味治疗感染后咳嗽的临床疗效。方法 将60例感染后咳嗽的患者随机分为对照组和治疗组,对照组单予经验性抗感染及止咳化痰治疗,治疗组在经验性抗感染及止咳化痰治疗的基础上,加用生脉散合当归补血汤加味方口服。观察2组患者在临床疗效、抗菌药物应用、不良反应、卫生经济学等方面的差异,评估2种方案的优劣。结果 与对照组相比,治疗组在咳嗽缓解时间、咳嗽治愈时间、总住院时间方面优于对照组;治疗组应用抗菌药物的时间短,明显低于对照组,且停用抗菌药物后咳嗽无反复;治疗组应用吸入性激素的时间明显短于对照组;在住院总费用和日均住院费用方面,治疗组明显低于对照组,差异均有统计学意义。治疗组口服药物后未出现不良反应,对照组共有5例患者出现不良反应。治疗组在3个月随访期间没有再次发生呼吸道感染,对照组有2例患者再次发生上呼吸道感染。结论 生脉散合当归补血汤加味方结合经验性抗感染及止咳化痰治疗方案治疗感染后咳嗽优于单纯抗感染及止咳化痰方案,是临床中治疗感染后咳嗽的优先选择。

Objective To observe the clinical effect of Shengmai powder and Danggui Buxue decoction on cough after infection.Methods Totally 30 patients with cough after infection were randomly divided into control group and treatment group.The control group was given empirical anti infection and antitussive and expectorant treatment,while the treatment group was given Shengmai powder and Danggui Buxue decoction on the basis of empirical anti infection and anti cough and expectorant treatment.The differences in clinical efficacy,application of antibiotics,adverse reactions and health economics between the two groups were observed,and the advantages and disadvantages of the two schemes were evaluated.Results Compared with the control group,the treatment group was better than the control group in terms of cough relief time,cough cure time and total hospital stay;the time of application of antibiotics in the treatment group was shorter than that in the control group,and there was no recurrence of cough after discontinuation of antibiotics;the time of inhalation of sex hormones in the treatment group was shorter than that in the control group.In terms of total hospitalization expenses and average daily hospitalization expenses,the treatment group was significantly lower than the control group,and the differences were statistically significant.There were no adverse reactions in the treatment group and 5 patients in the control group.During the 3-month follow-up period,no respiratory tract infection occurred again in the treatment group,and 2 cases of upper respiratory tract infection occurred again in the control group.Conclusion Shengmai powder and Danggui Buxue decoction combined with empirical anti infection and antitussive and expectorant treatment is better than simple anti infection and antitussive and expectorant treatment,and it is the preferred choice in clinical treatment of cough after infection.