摘要
本文对全球锂资源的分布及锂在人体内的吸收、分布、代谢与排泄进行了介绍,阐述了环境中的锂对神经系统的积极作用和锂的神经保护作用机制。通过食物链进入人体的微量锂可对机体健康产生有益影响,诸如改善认知能力、降低抑郁和暴力倾向。但是,锂的安全剂量范围较窄,在高锂地区,饮用较高浓度的锂水对人体健康的影响尚不明确。研究不同剂量的锂,尤其是环境高浓度剂量锂对机体的健康效应及其作用机制是很有必要的。
This paper introduces the distribution of global lithium resources and absorption,distribution,metabolism and excretion of lithium in the human body,discussing the positive effect of lithium in the environment on the nervous system and its neuroprotective mechanism.The tiny amounts of lithium that enter the body through the food chain have been linked to beneficial health effects,such as improved cognition and reduced depression and violence.However,the safe dose range of lithium is narrow,and the health effects of drinking high concentrations of lithium water in high-lithium areas are unclear.It is necessary to study the health effects and mechanisms of different doses of lithium,especially high concentrations of lithium in the environment.
作者
王钜铃
金永堂
Wang Juling;Jin Yongtang(Environmental Epigenetics Laboratory,School of Public Health,Zhejiang University,Hangzhou 310058,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2022年第3期233-239,共7页
Chinese Journal of Preventive Medicine
基金
国家自然科学基金(81673124)。
关键词
锂
环境
中枢神经系统
健康效应
机制
Lithium
Environment
Central nervous system
Health effects
Mechanism