基于CiteSpace的我国药品综合评价研究现状分析

Analysis of current situation of researches on comprehensive evaluation of drugs in China based on CiteSpace

目的 分析我国药品综合评价研究的现状。方法 运用文献计量学的方法,借助CiteSpace 5.8.R3分析工具,对中国知网中有关药品安全性、有效性、经济性、创新性、适宜性、可及性6个维度文献的研究现状和研究热点进行汇总。结果与结论 目前,有关药品安全性和有效性的研究较多,经济性评价研究逐渐增加,而综合6个维度进行药品综合评价的相关研究仍不多见。研究者较为集中,而研究者之间和研究机构之间的合作较少。研究方法以系统综述、Meta分析、临床观察性研究和回顾性研究较为多见;研究药物以抗菌药物、抗肿瘤药和心血管系统疾病药物较为热门。建议建立药品临床综合评价的统一方法和标准,明确药品临床综合评价工作的协调机制,充分运用真实世界数据丰富6个维度内容,对评价各环节实施质量控制,形成证据充分、结果确定的综合性评价报告,推动结果的临床应用。

OBJECTIVE To analyze the situation of comprehensive drug evaluation research in China. METHODS Using the method of bibliometrics,CiteSpace 5.8.R3 analysis tool was used to summarize the research situation and hotspots from 6dimensions,such as safety,effectiveness,economy,innovation,suitability and accessibility. RESULTS & CONCLUSIONS At present,there were many types of researches on safety and effectiveness. The economic evaluation was increasing. There were still not much researches on the comprehensive evaluation of drugs from 6 dimensions. Researchers were concentrated,and there was less collaboration between researchers or research institutions. In terms of methods,systematic review,meta-analysis,clinical observational research and retrospective research were more common. The topic selection of antibacterial drugs,anti-tumor drugs,and cardiovascular drugs were more popular. It is recommended to establish a unified method and standard for clinical comprehensive evaluation of drugs,clarify the coordination medianism of the comprehensive drug evaluation,make full use of realworld data to enrich the contents of 6 dimensions,implement quality control for all segments of the evaluation,and form a comprehensive evaluation report with sufficient evidence and definite results,so as to promote the clinical application of the results.