卒中后抑郁与高死亡风险研究进展

Research progress on the correlation between PSD and high risk of death

脑卒中是脑缺血性或出血性改变造成的脑部功能缺损的临床疾病,卒中后抑郁(post stroke depression,PSD)是卒中后神经精神障碍中最常见的并发症。随着医学的发展,科研工作者对PSD的认识逐渐加深,也认识到其会严重影响脑卒中患者的生活质量,且患有抑郁症的患者较卒中后非抑郁患者死亡风险明显升高。本文针对性探讨了PSD患者的临床表现、诊断标准、危险因素、高死亡风险的可能原因和治疗、预防的方法进行综述,为促进医务工作者的临床工作效率和PSD患者的临床疗效提供理论支持。

Post-stroke depression(PSD)is the most common complication of post-stroke neuropsychiatric disorders,in which,brain function is impaired due to cerebral ischaemic or haemorrhagic changes.With the development of medicine,researchers have become more aware of PSD and the fact that PSD can seriously affect the life quality of patients with cerebral stroke.Moreover the risk of death in patients with depression after stroke is significantly higher than that in patients without depression after stroke.This article reviews the clinical presentation,diagnostic criteria,risk factors,possible causes of high mortality risk,treatment and prevention of PSD,so as to provide theoretical support for improving the clinical efficiency of doctors and the therapeutic effects on PSD.