邢台地区乳腺癌发病的影响因素分析

The influencing factors of pathogenesis of of breast cancer in Xingtai area

目的探索邢台地区乳腺癌发病的影响因素,为降低乳腺癌的发病率提供依据。方法选取2019年6月至2020年6月首次确诊的乳腺癌患者210例为观察组,同期体检中心体检的女性,按照1∶1匹配选入对照组210例,调查2组人群的一般情况、月经和生育史、既往史、个人史、家族史及饮食情况,分析影响乳腺癌发病的因素。结果影响乳腺癌发生的因素有超重(OR=1.960,95%CI:1.191~3.225)、肥胖(OR=3.242,95%CI:1.207~8.707)、月经初潮年龄(OR=0.471,95%CI:0.231~0.961)、有生育者首次足月产年龄(OR=1.995,95%CI:1.169~3.404)、母乳喂养(OR=0.429,95%CI:0.212~0.867)、乳腺癌家族史(OR=7.391,95%CI:2.215~24.667)、偶尔食用油炸食品(OR=0.136,95%CI:0.091~0.205)和从不食用油炸食品(OR=0.128,95%CI:0.087~0.189)、从不食用腌制食品(OR=0.141,95%CI:0.095~0.209)。结论超重和肥胖、有生育者首次足月产年龄越大、有乳腺癌家族史是乳腺癌的危险因素;月经初潮年龄大、有母乳喂养、偶尔和从不食用油炸食品、从不食用腌制食品是乳腺癌的保护因素。

Objective To investigate the influencing factors of pathogenesis of of breast cancer in Xingtai area,so as to provide basis for reducing the incidence of breast cancer in Xingtai area.Methods A total of 210 patients with breast cancer who were treated in our hospital were enrolled as observation group,at the same time,the other 210 subjects who underwent physical examination were enrolled as control group.The general conditions,menstrual and reproductive history,history of past illness,personal history,family history and dietary status were observed and compared between the two groups.Moreover the influencing factors on the pathogenesis of breast cancer were analyzed.Results The influencing factors on the pathogenesis of breast cancer were overweight,obesity(OR=1.960,95%CI;1.191~3.225),age of menarche(OR=0.471,95%CI;0.231~0.961),age of first term birth(OR=1.995,95%CI;1.169~3.404),breast feeding(OR=0.429,95%CI;0.212~0.876),family history of breast cancer(OR=7.391,95%CI;2.215~24.667),occasionally eating fried food(OR=0.136,95%CI;0.091~0.205),never eating fried food,never eating preserved food(OR=0.141,95%CI;0.095~0.209).Conclusion The overweight and obesity,the older women with first term birth and having family history of breast cancer are risk factors of breast cancer,however,the older age at menarche,breast feeding,occasional and never eating fried foods,never eating preserved foods are protective factors of breast cancer.