重复经颅磁刺激联合丁苯酞治疗脑卒中研究

Repetitive Transcranial Magnetic Stimulation Combined with Butylphthalide in the Treatment of Stroke

目的研究脑卒中患者接受重复经颅磁刺激(rTMS)和丁苯酞联合治疗的临床效果。方法本研究对象选取2018年5月至2019年9月期间,我院收治的脑卒中患者100例进行回顾性研究。根据治疗方式分为对照组和研究组,各50例。对照组给予丁苯酞治疗,实验组在对照组基础上增加rTMS治疗,比较两组患者治疗效果。结果治疗后两组患者血清NSE、S100B和GFAP指标较治疗前均明显降低(P<0.05),且治疗后实验组三项血清指标明显优于对照组(P<0.05)。实验组总有效率(96.0%)明显高于对照组(86.0%),差异显著,有统计学意义(P<0.05)。两组均未出现严重不良反应。结论重复经颅磁刺激联合丁苯酞治疗脑卒中患者,可有效降低血清NSE、S100B和GFAP水平,提高治疗总有效率。

Objective To study the clinical effect of repeated transcranial magnetic stimulation combined with butylphthalide in stroke patients.Methods A retrospective study was conducted on 100 stroke patients admitted to our hospital from May 2018 to September 2019.According to the treatment methods,the patients were divided into control group and study group,50 cases in each group.The control group was given butylphthalide treatment,and the experimental group was added with repeated TRANSC ranial magnetic stimulation on the basis of the control group,and the therapeutic effects of the two groups were compared.Results After treatment,the serum NSE,S100B and GFAP indexes in 2groups were significantly lower than those before treatment(P<0.05),and the three serum indexes in experimental group were significantly better than those in control group(P<0.05).The total effective rate of the experimental group(96.0%)was significantly higher than that of the control group(86.0%),the difference was statistically significant(P<0.05).There were no serious adverse reactions in both groups.Conclusion Repeated TRANSCranial magnetic stimulation combined with butylphthalide can effectively reduce serum LEVELS of NSE,S100B and GFAP in stroke patients,and improve the total effective rate.