药物预防创伤后应激性溃疡的临床效果探讨

Clinical effect of drugs prevention of post-traumatic stress ulcer

目的以预防创伤后应激性溃疡为目标,探究不同药物的预防效果。方法将2020—2021年间收治的100例重度创伤患者基于抽样法均分两组,对照组给予奥美拉唑,观察组给予泮托拉唑。比较两组差异。结果观察组比对照组应激性溃疡发生率低(4%:18%,P<0.05),不良症状发生率相近(6%:12%,P>0.05)。结论奥美拉唑、泮托拉唑均可预防创伤后应激性溃疡,但后者预防效果更好。

Objective To explore the preventive effect of different drugs in the prevention of post-traumatic stress ulcer.Methods A total of 100 patients with severe trauma admitted from 2020 to 2021 were randomly divided into two groups based on sampling method.The control group was given omeprazole,and the observation group was given pantoprazole.Compare the differences between the two groups.Results The incidence of stress ulcer in the observation group was lower than that in the control group(4%:18%,P<0.05),and the incidence of adverse symptoms was similar(6%:12%,P>0.05).Conclusion Both omeprazole and pantoprazole can prevent post-traumatic stress ulcer,but the latter has better preventive effect.