高通量血液透析对尿毒症患者的影响

Effect of high-throughput hemodialysis on patients with uremia

目的分析对尿毒症患者实施高通量血液透析的效果。方法抽取我院2019年收治的尿毒症患者62例作为研究对象,并根据随机数字表法分为对照组和研究组。对照组常规血液透析,研究组高通量血液透析,比较两组透析效果。结果炎症因子水平,治疗前两组相近(P>0.05),差异无统计学意义,治疗后研究组超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均低于对照组[(9.45±5.32)VS(18.98±5.71)],[(193.46±26.37)VS(342.35±27.64)],[(4.12±0.90)VS(9.27±1.98)],差异有统计学意义(P<0.05);血尿毒素水平治疗前两组相近(P>0.05),治疗后研究组血尿素氮(BUN)以及肌酐(Scr)水平均低于对照组[(7.12±0.84)VS(9.33±1.14)],[(200.33±4.17)VS(260.26±4.39)],差异有统计学意义(P<0.05)。结论对尿毒症患者实施高通量血液透析的价值较高,可推广。

Objective To analyze the effect of high-throughput hemodialysis in patients with uremia.Methods Taking 62 uremia patients between January and December 2019 as observed and dividing were divided equality into control and study groups according to random digital table.Control group had routine hemodialysis,and study group had high-throughput hemodialysis and comparing different dialysis effects.Results Inflammatory levels of inflammatory factors,no significant difference before treatment(P>0.05),lower hs-CRP,IL-6 and TNF-αlevels in the control group,not(P<0.05),blood urea nitrogen,creatinine,not before treatment(P>0.05),and BUN and Scr levels were lower than the control group(P<0.05).Conclusion The implementation of high-throughput hemodialysis in uremia patients is of high value and canbe promoted.