重组人干扰素α-2b联合宫颈炎康栓治疗慢性宫颈炎的临床效果观察

Clinical effect of recombinant human interferonα-2b and cervicitis kang bolt on chronic cervicitis

目的:观察在慢性宫颈炎患者治疗中使用重组人干扰素α-2b联合宫颈炎康栓的治疗效果。方法:选取2019年4月—2021年6月广东医科大学附属惠东医院接受治疗的66例慢性宫颈炎患者,用随机数字表法分为对照组和观察组各33例,对照组实施重组人干扰素α-2b治疗,观察组实施重组人干扰素α-2b联合宫颈炎康栓治疗法。比较两组治疗前后T淋巴细胞免疫功能指标、临床症状改善时间、治疗有效率、不良反应发生率。结果:治疗前,两组T淋巴细胞免疫功能指标对比无显著差异(P>0.05);治疗后,观察组T淋巴细胞免疫功能指标高于对照组,临床症状改善时间低于对照组,临床治疗总有效率高于对照组,不良反应总发生率低于对照组,差异均有统计学意义(P<0.05)。结论:在慢性宫颈炎疾病治疗中使用重组人干扰素α-2b联合宫颈炎康栓治疗方法,有助于改善患者免疫功能,缩短临床症状改善时间,降低不良反应发生率,提升疾病临床治疗效果。

Objective The therapeutic effect of using recombinant human interferon-2b combined with cervicitis kang plugs in patients with chronic cervitis was observed.Methods 66 patients with chronic cervicitis treated in Huidong Hospital affiliated to Guangdong Medical University from April 2019 to June 2021 were selected.Random digital method was divided into 33 patients in the observation group.recombinant human interferon-2b treatment was used in the control group,and recombinant human interferon-2b combined with cervicitis thrombolytic therapy was used in the observation group.Tlymphocyte immune function indicators,time of clinical symptom improvement,treatment efficiency and incidence of adverse reactions were used before and after treatment and compared between the two groups.Results Before treatment,comparison of T lymphocytes(P>0.05);After treatment,T lymphocytes was higher than control,improvement time of clinical symptoms was lower than control,clinical treatment was more efficient than control,and incidence of adverse reactions was lower than control(P<0.05).Conclusions Using recombinant human interferon-2b combined with cervicitis in chronic cervicitis disease helps to improve patient immune function,shorten the improvement time of clinical symptoms,reduce the incidence of adverse reactions,and improve the clinical treatment effect of the disease.