摘要
目的探讨补阳还五汤的应用对全膝关节置换患者术后凝血功能及膝关节功能的影响。方法选取2018年3月至2020年3月在河南省直第三人民医院接受治疗的120例全膝关节置换患者作为研究对象,根据随机数字表法将患者分为两组,分别命名为对照组(n=60)与观察组(n=60),对照组采用传统西药治疗,观察组采用补阳还五汤进行治疗,对两组凝血功能指标、膝关节功能评分以及不良反应发生率进行对比。结果治疗后观察组患者D-二聚体(D-D)指标低于对照组,活化部分凝血酶原时间(APTT)、凝血酶原时间(PT)长于对照组,差异有统计学意义(P<0.05)。治疗后观察组患者膝关节功能评价分数高于对照组,差异有统计学意义(P<0.05)。观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论在全膝关节置换患者术后治疗中,补阳还五汤的应用有着较好效果,对凝血功能有着一定的改善作用,能够降低不良反应发生率,更好地促进患者膝关节功能的恢复。
Objective To explore the effect of Buyang Huanwu Decoction on coagulation function and knee joint function in patients with total knee arthroplasty.Methods A total of 120 patients with total knee arthroplasty treated in our hospital from March 2018 to March 2020 were selected as the research objects,and the patients were divided into two groups according to the random number table method,named as the control group(n=60)and the observation group(n=60),the control group was treated with traditional western medicine,and the observation group was treated with Buyang Huanwu Decoction.The coagulation function indexes,knee joint function scores and the incidence of adverse reactions were compared between the two groups.Results After treatment,the D-dimer(DD)index in the observation group was lower than that in the control group,and the activated partial prothrombin time(APTT)and prothrombin time(PT)were longer than those in the control group,with statistical significance(P<0.05).After treatment,the knee joint function evaluation scores in the observation group were higher than those in the control group,with statistical significance(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,with statistical significance(P<0.05).Conclusion In the postoperative treatment of patients with total knee arthroplasty,the application of Buyang Huanwu Decoction has a good effect,which can improve the coagulation function to a certain extent,reduce the incidence of adverse reactions,and better promote the recovery of patients’knee function.
作者
孙晓
张保安
张盾盾
刘强
熊小云
杨曼
段春天
刘会星
SUN Xiao;ZHANG Baoan;ZHANG Dundun;LIU Qiang;XIONG Xiaoyun;YANG Man;DUAN Chuntian;LIU Huixing(Department of Rehabilitation Medicine,the Third People’s Hospital of Henan Province,Zhengzhou Henan 450000,China)
出处
《临床研究》
2022年第3期129-132,共4页
Clinical Research
基金
感觉运动训练对膝关节置换患者功能和平衡能力影响的研究(2018020579)。
关键词
全膝关节置换
补阳还五汤
凝血功能
膝关节功能
total knee replacement
Buyang Huanwu Decoction
coagulation function
knee joint function