间歇性断食对超重肥胖者的减肥效果研究

Study on the effectiveness of intermittent fasting on weight loss in overweight and obese people

目的探讨间歇性断食(IF)对超重肥胖者的减肥效果,研究减肥期间体重、血糖及血脂等变化,为减肥提供新方法。方法2020年7~12月,用随机对照试验法,将招募到的超重肥胖志愿者54人,随机分为间歇性断食组(IF组28人)和对照组(CT组26人)。干预20周后,比较两组体重、血糖和血脂等指标变化。用SPSS 17.0软件统计分析。结果IF组体重、BMI、腰臀围、血糖、低密度脂蛋白胆固醇水平均低于CT组;BMI分层分析结果显示,IF组超重和肥胖组干预后的体重、BMI、腰围和臀围均低于干预前,超重组干预后血糖低于干预前,肥胖组干预后HDL-C高干预前。多元线性回归分析显示,BMI与腰围、TG指标的线性关系,复相关系数R=0.64。结论间歇性断食除了可有效降低超重肥胖者的体重和BMI外,还可降低血脂、血糖水平,提示间歇性断食是一种有效的减肥方案。

Objective To explore the effectiveness of intermittent fasting(IF)on weight loss in overweight and obese people,and study the changes of body weight,blood glucose and blood lipids during weight loss period for developing a new method.Methods Totally 54 overweight and obese volunteers were recruited and randomly divided into intermittent fasting group(28 cases for IF group)and control group(26 cases for CT group)by randomized controlled trial from Jul.to Dec.2020.The changes of body weight,blood glucose and blood lipid were compared between the two groups after 20 weeks of intervention and SPSS 17.0 package was used for statistical analysis.Results The levels of body weight,BMI,waist hip circumference,blood glucose and low density lipoprotein cholesterol in IF group were lower than those in CT group.The results of BMI stratified analysis showed that the weight,BMI,waist and hip circumference of overweight and obese groups in the IF group were lower than those before intervention,blood glucose was lower after intervention,and HDL-C in the obese group after intervention was higher than that before intervention.Multiple linear regression analysis showed that there existed a linear relationship between BMI and waist circumference and TG,the multiple correlation coefficient R=0.64.Conclusion In addition to reducing the body weight and BMI of overweight and obese people,intermittent fasting can also reduce blood lipid and blood glucose levels,suggesting that intermittent fasting is an effective weight loss program.