摘要
将蒙脱石(MMT)引入聚醚醚酮(PEEK)用于增强PEEK的生物活性,并采用选择性激光烧结(SLS)制备PEEK/MMT复合支架。体外矿化实验结果表明:磷灰石在PEEK/MMT支架上的沉积得到了显著改善,支架的断裂模式从脆性断裂向韧性断裂转变。在磷酸缓冲溶液(PBS)中的降解实验发现,PEEK/MMT复合支架上出现不均匀的孔洞,这归因于MMT对加速降解起的积极作用。因而,复合支架显示了良好的生物活性。
Montmorillonite(MMT)was introduced into polyetheretherketone(PEEK)to enhance the bioactivity of PEEK,and selective laser sintering(SLS)was used to prepare PEEK/MMT composite scaffolds.The results of in vitro mineralization experiments showed that the deposition of apatite on PEEK/MMT scaffolds was significantly improved,and the fracture mode of the scaffolds changed from brittle to ductile.Besides,the degradation experiments in phosphate buffered solution(PBS)found that uneven pores appeared on the PEEK/MMT composite scaffolds,which was attributed to the positive effect of MMT on accelerated degradation.Thus,the composite scaffold showed good biological activity.
作者
李冬英
李品
王浩宇
徐勇
陈玫瑰
杜浩城
LI Dongying;LI Pin;WANG Haoyu;XU Yong;CHEN Meigui;DU Haocheng(School of Mechanical and Energy Engineering,Shaoyang University,Shaoyang 422000,China)
出处
《邵阳学院学报（自然科学版）》
2022年第2期45-52,共8页
Journal of Shaoyang University：Natural Science Edition
基金
湖南省自然科学基金(2021JJ30632,2020JJ4556)
湖南省教育厅创新平台开放基金(18A384,19K083,21B0686)
邵阳学院研究生创新项目(CX2020SY024,CX2020SY026,CX2020SY022)。
关键词
聚醚醚酮
蒙脱石
复合支架
选择性激光烧结
生物活性
polyetheretherketone
montmorillonite
composite scaffold
selective laser sintering
bioactivity
