无创通气对急性心源性肺水肿患者血气指标、并发症及预后的影响

Effect of Non-invasive Ventilation on Blood Gas Indexes,Complications and Prognosis of Patients with Acute Cardiogenic Pulmonary Edema

目的探讨对急性心源性肺水肿采用无创机械通气治疗对改善患者血气指标,预防并发症发生以及改善患者预后的作用。方法选取2019年1月—2020年12月该院ICU收治的急性心源性肺水肿患者70例,以随机数表法将患者分为采用常规治疗的对照组(n=35)与联合无创机械通气治疗的研究组(n=35),比较两组治疗前后血气指标,并发症发生情况,预后情况。结果治疗后,研究组氧分压、碱剩余水平分别为(81.60±10.25)mmHg、(-2.64±0.70)mmol/L,对照组氧分压、碱剩余水平分别为(66.95±12.07)mmHg、(-3.82±0.67)mmol/L;研究组均高于对照组,差异有统计学意义(t=5.473、7.205,P<0.05)。研究组二氧化碳分压、乳酸水平分别为(35.36±5.84)mmHg、(2.29±0.62)mmol/L,对照组二氧化碳分压、乳酸水平分别为(41.60±6.58)mmHg、(3.15±0.65)mmol/L,研究组均低于对照组,差异有统计学意义(t=4.196、5.664,P<0.05)。研究组并发症发生率为5.71%,对照组并发症发生率为25.71%,研究组低于对照组;研究组治疗总有效率为97.14%,高于对照组(74.29%),差异有统计学意义(χ^(2)=5.285、7.467,P<0.05)。结论对心源性肺水肿患者采用无创机械通气方案治疗能够有效改善患者的血气指标,可降低并发症发生率,有利于改善预后,值得推广。

Objective To explore the effect of non-invasive mechanical ventilation in the treatment of acute cardiogenic pulmonary edema in improving blood gas indicators,preventing complications and improving the prognosis of patients.Methods Selected 70 patients with acute cardiogenic pulmonary edema admitted to the ICU of this hospital from January 2019 to December 2020.The patients were divided into the control group treated with conventional treatment(n=35)and the study group combined non-invasive mechanical ventilation treatment(n=35)according to the random number table method.The blood gas indexes,complication rate,the prognosis of the two groups before and after treatment were compared.Results After treatment,the partial pressure of oxygen and residual alkalinity levels in the experimental group were(81.60±10.25)mmHg and(-2.64±0.70)mmol/L,respectively;the oxygen partial pressure and residual alkalinity levels in the control group were(66.95±12.07)mmHg,(-3.82±0.67)mmol/L;the study group were higher than those of the control group,and the difference was statistically significant(t=5.473,7.205,P<0.05).The partial pressure of carbon dioxide and lactic acid levels in the study group were(35.36±5.84)mmHg and(2.29±0.62)mmol/L,respectively;the partial pressure of carbon dioxide and lactic acid levels in the control group were(41.60±6.58)mmHg and(3.15±0.65)mmol/L,respectively;the study group were lower than those of the control group,and the difference was statistically significant(t=4.196,5.664,P<0.05).The complication rate of the study group was 5.71%,and that of the control group was 25.71%;the study group was lower than the control group;the total effective rate of treatment in the study group was 97.14%,which was higher than 74.29%in the control group,the difference was statistically significant(χ^(2)=5.285,7.467,P<0.05).Conclusion The treatment of patients with cardiogenic pulmonary edema using non-invasive mechanical ventilation can effectively improve the blood gas indicators of the patients,reduce the incidence of complications,and improve the prognosis.It is worthy of promotion.