生活方式相关性干眼的研究进展

Progress of research on lifestyle-related dry eye

干眼是常见的眼表慢性疾病,是多种因素导致的泪膜不稳定和眼表微环境失衡,从而引起各种症状和/或视力障碍,并可能同时伴有眼表损伤的疾病。近年来,随着生活方式和环境等多种因素的改变,干眼的发病率逐年增加。既往关于干眼致病因素的研究多集中于器质性因素,然而近年研究发现,非器质性因素对干眼的发生也有不可忽视的作用。本文介绍了近年来国内外生活方式相关性干眼的患病情况,并综述了导致生活方式相关性干眼的主要危险因素和相应预防措施。

Dry eye is a common chronic disease in the ocular surface,expressed by the instability of the tear film and the imbalance of the ocular surface microenvironment due to various factors,which can cause various symptoms and/or visual impairment,and may be accompanied by ocular surface damage.In recent years,with changes in lifestyle and environment,the incidence of dry eye has increased year by year.Previous studies on the pathogenesis of dry eye mostly focused on organic factors.However,recent studies have found that non-organic factors also play a major role in the occurrence of dry eye.This article introduces the prevalence of dry eye related to lifestyles at home and abroad in recent years and summarizes the main risk factors that lead to lifestyle-related dry eye and preventive interventions.