小儿急性腹泻病血清白蛋白检测临床探讨

Clinical Study on Detection of Serum Albumin in Children with Acute Diarrhea

目的探究小儿急性腹泻病血清白蛋白检测的价值。方法随机选取江苏省泗洪县第一人民医院儿科2018年1月—2020年1月收治的小儿急性腹泻患者100例为研究对象,根据其是否合并脓毒症、是否合并轻度胃肠炎伴良性婴幼儿惊厥(BICE)、不同住院时间(<7 d或≥7 d)、不同简易小儿危重症评分(简易PCIS评分)进行分组,即脓毒症组(n=28)、无脓毒症组(n=72),住院时间<7 d组(n=82)、≥7 d组(n=18),简易PCIS评分>72分组(n=84)、≤72分组(n=16),合并惊厥组(n=14)、未合并惊厥组(n=86),均为其实施血清白蛋白检测,对不同组患者血清白蛋白检测的结果进行分析。结果脓毒症组、住院时间≥7 d组、简易PCIS评分≤72分组小儿急性腹泻病患者的血清白蛋白水平分别为(36.98±2.67)、(38.02±2.69)、(36.78±2.54)g/L,均低于无脓毒症组、住院时间<7 d组、简易PCIS评分>72分组,差异有统计学意义(t=4.168、4.119、3.468,P<0.05);合并惊厥组与未合并惊厥组患者的血清白蛋白水平相比,差异无统计学意义(t=0.387,P>0.05)。结论为小儿急性腹泻病患者实施血清白蛋白水平的检测,可对其病情进行反映,指导患者接受更加有效的治疗干预,以此改善其预后。

Objective To explore the value of serum albumin detection in children with acute diarrhea.Methods From January 2018 to January 2020,a total of 100 pediatric patients with acute diarrhea in the Department of Pediatrics,First People's Hospital of Sihong County,Jiangsu Province,were taken as the research object.According to whether they were combined with sepsis,whether they were combined with mild gastroenteritis with benign infantile convulsions(BICE),different length of stay(<7 d or≥7 d),and different simple pediatric critical illness score(PCIS)scores were divided into groups.That was,the sepsis group(n=28),the non-sepsis group(n=72),the hospitalization time<7 d group(n=82),the≥7 d group(n=18),simple PCIS scores>72 groups(n=84),≤72 groups(n=16),combined seizure group(n=14),non-combined seizure group(n=86).They all carried out serum albumin testing,to analyze the results of serum albumin testing in different groups of patients.Results The serum albumin levels of children with acute diarrhea in the sepsis group,hospitalization time≥7 d group,and simple PCIS score≤72 group were(36.98±2.67)g/L,(38.02±2.69)g/L,(36.78±2.54)g/L,all lower than the non-sepsis group,hospitalization time<7 d group,simple PCIS score>72 groups,the difference was statistically significant(t=4.168,4.119,3.468,P<0.05);there was no statistically significant difference in serum albumin levels between the patients with convulsions and those without convulsions(t=0.387,P>0.05).Conclusion In children with acute diarrhea,the detection of serum albumin level can be used to reflect the condition,guide the patient to receive more effective treatment interventions,and improve their prognosis.