癌症患者化疗与卒中

Chemotherapy and stroke in cancer patients

癌症患者化疗与卒中存在一定的关系,其机制可能与化疗增高传统血管因素患病率、促进凝血功能障碍、诱发贫血以及引起心功能受损和血管炎症有关。化疗相关卒中的病理生理学机制目前仍处于探索阶段。文章对癌症患者化疗过程中出现的卒中的相关病理生理学机制、监测指标以及诊断和治疗进展进行了综述。

There is a certain relationship between chemotherapy and stroke in cancer patients.Its mechanism may be associated with the increase of the prevalence of traditional vascular factors,the promotion of coagulation dysfunction,the induction of anemia,the impairment of cardiac function,and vascular inflammation.The pathophysiological mechanism of chemotherapy-associated stroke is still in the exploratory stage.This article reviews the pathophysiological mechanism,monitoring indicators,and diagnosis and treatment progress of stroke in cancer patients during chemotherapy.