炎症性肠病相关认知障碍的诊疗进展

The diagnosis and treatment progress of cognitive dysfunction in inflammatory bowel diseases

炎症性肠病(IBD)常伴发各种神经系统并发症,包括周围神经疾病、脑血管疾病、中枢脱髓鞘疾病、偏头痛等。新近的研究表明,IBD患者认知功能较健康人群明显受损。然而,目前IBD相关认知障碍的研究较少。通过探讨IBD相关认知障碍的发病机制、临床表现、辅助检查和诊疗策略,旨在加深临床医师对此类疾病的认识和理解,并为其预防和治疗提供新的靶点和方向。

Inflammatory bowel diseases(IBD)are always accompanied by a series of neurological complications,including peripheral neuropathy,cerebrovascular diseases,demyelinating diseases of the central nervous system,migraine,etc.Recent studies demonstrated that the cognitive function of IBD patients is significantly impaired than that of healthy people.However,IBD-related cognitive impairment is little known.This review aims to explore the pathogenesis,clinical manifestation,examination and treatment strategy of IBD-related cognitive impairment,which may contribute to enhance clinicians'knowledge and understanding of these diseases,furthermore,provide a novel target and orientation for their prevention and therapy.