无抽搐电休克治疗对抑郁症患者自伤行为的影响

Effect of modified electroconvulsive therapy on self injury behavior in patients with depression

目的:探讨无抽搐电休克治疗(MECT)对抑郁症患者自伤行为的疗效。方法:采用对照研究设计,根据伴有自伤行为的抑郁症患者是否同意接受MECT的意愿将其分为研究组(共43例)和对照组(共42例);两组患者在服用抗抑郁药治疗的基础上,给予研究组每周3次MECT,共9次,刺激部位为双侧颞叶。治疗前及治疗后6个月采用自伤行为问卷对两组患者进行自伤行为方式及频率进行评估。结果:与治疗前相比,干预6个月后研究组与对照组自伤频率均显著降低,且研究组明显低于对照组(P均<0.01);与对照组相比,干预6个月后研究组自伤行为方式显著少于对照组。结论:MECT能有效减少抑郁症患者自伤行为。

Objective:To explore the effect of Modified Electroconvulsive Therapy(MECT)on self injury behavior in patients with depression.Method:A controlled study design was used,patients were assigned into research group(43 cases)and control group(42 cases in total)according to their willingness.All patients recieved antidepressants treatment,while the research group were given additional bilateral MECT for three times a week,9 times in total.Self injury behavior questionnaire was used to evaluate the self injury behavior styles and frequencies before and 6 months after therapy.Results:Compared with the baseline,self injury frequencies of the research group and the control group were significantly decreased after 6 months'therapy(P<0.01).Compared with the control group,the self injury styles in the research group was significantly lower after 6 months'therapy.Conclusion:MECT is effective in treating self-injury behavoirs in depression patients.