摘要
目的:探讨颈动脉蹼(CW)血流动力学变化与缺血性脑卒中的关系。方法:结合计算流体力学总结并分析1例CW导致的急性缺血性脑卒中的临床病例资料并回顾相关文献。结果:通过计算流体力学结合文献分析,CW所处位置存在二次流漩涡,低壁面剪切力(WSS)、低剪切力震荡因子(OSI)、高相对滞留时间(RRT)可能是刺激血栓形成的因素,从而增加急性缺血性脑卒中的风险。结论:CW血流动力学变化是缺血性脑卒中发生的重要机制。
Objective:To investigate the relationship between the changes of carotid web hemodynamics and ischemic stroke.Methods:A case of acute ischemic stroke involved in carotid web artery was retrospectively analyzed by computational fluid dynamics(CFD),and related literatures were reviewed.Results:CFD analysis,together with review of the related literatures,demonstrated that presence of secondary flow vortexes at the location of carotid web,low wall shear stress(WSS),low shear force shock factor(OSI)and high relative residence time(RRT)were potential factors stimulating thrombosis,thus increasing the risk of acute ischemic stroke.Conclusion:The change of carotid web hemodynamics is an important mechanism of ischemic stroke.
作者
苗壮
黄显军
干伟鹏
杨倩
MIAO Zhuang;HUANG Xianjun;GAN Weipeng;YANG Qian(Medical Imaging Center,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China)
出处
《皖南医学院学报》
CAS
2022年第2期202-204,共3页
Journal of Wannan Medical College
基金
皖南医学院中青年科研基金项目(WK2019F22)。
关键词
颈动脉蹼
脑卒中
计算流体力学
carotid web
stroke
computational fluid dynamics