摘要
Electrospun sodium alginate(SA)fibers,which are always considered as a kind of biocompatible and non-toxic materials,have great potential application in the biomedical field due to high specific surface area and large porosity.However,in order to facilitate the electrospinning process,another polymer should be added into the SA solution.The effect of the added polymer of polyethylene oxide(PEO),SA,and ethanol on tuning the beaded structure of electrospun fibers was evaluated.Pure SA electrospun membrane with a beaded structure was prepared.The results show that PEO can facilitate the fabrication,but the mass fractions of SA and ethanol are positively correlated with the bead forming.When the mass fraction of ethanol in the solution was 15.0%(mass fractions of SA and PEO were 1.0%and 1.5%,respectively),the average diameter of the obtained beads was 824.80 nm,and the average length was 2.88μm.Besides,the fibrous structure can be maintained even after the removal of PEO by ethanol.After removing PEO,the average diameter of the beads was reduced to 578.73 nm and the average length was reduced to 2.34μm.
基金
Fundamental Research Funds for the Central Universities of China(No.2232019D3-15)。
