消瘿清热汤联合穴位注射治疗甲亢伴胫前黏液性水肿临床观察

Clinical Observation on Xiaoying Qingre Decoction Combined with Acupoint Injection on Hyperthyroidism Patients with Pretibial Myxedema

目的系统性评估消瘿清热汤联合穴位注射治疗对甲状腺功能亢进症(简称甲亢)伴胫前黏液性水肿患者的临床效果。方法选取自2019年5月—2020年5月于抚顺市中医院内分泌科病房住院并接受治疗的甲亢伴胫前黏液性水肿患者60例,入组病例均采用信封法随机分为对照组和试验组。对照组30例,应用甲巯咪唑内服联合穴位注射治疗方案,试验组30例,在对照组基础上联合消瘿清热汤内服治疗方案,观察2组患者治疗前后中医证候积分、甲状腺激素水平及胫前黏液性水肿皮损面积变化情况。结果经临床治疗,试验组中医证候评分、T3激素、T4激素、皮损面积均优于对照组,差异有统计学意义(P<0.05)。结论消瘿清热汤联合穴位注射可显著稳定患者甲状腺素水平,滋阴清热、散结解郁、养血消瘿,临床效果显著,值得临床推广。

Objective To systematically evaluate the clinical effect of Xiaoying Qingre decoction combined with acupoint injection on hyperthyroidism patients with anterior tibial myxedema.Methods From May 2019 to May 2020,60 patients with hyperthyroidism complicated with anterior tibial myxedema in Fushun Hospital of Traditional Chinese Medicine were selected and randomly divided into control group and experimental group by envelope method.The control group(30 cases)was treated with methimazole combined with acupoint injection,while the experimental group(30 cases)was treated with Xiaoying Qingre decoction on the basis of the control group.The traditional Chinese medicine(TCM)syndrome score,thyroid hormone level and skin lesion area of anterior tibial myxedema were observed before and after treatment.Results After clinical treatment,TCM symptom score,T3,T4 and lesion area of the experimental group were better than those of the control group,and the difference had statistical significance(P<0.05).Conclusion Xiaoying Qingre decoction combined with acupoint injection can significantly stabilize the thyroid hormone level of patients,nourish yin,clear heat,relieve depression,nourish blood and eliminate gall,which has significant clinical effect and is worthy of clinical promotion.