抗甲协定方与西药联合治疗甲状腺机能亢进的临床观察

Clinical observation on the treatment of hyperthyroidism with the combination of antithyroid and Western medicine

目的:分析研究在甲状腺机能亢进患者的治疗中,使用抗甲协定方与西药联合治疗的临床效果。方法:使用简单随机抽样法从2018年5月至2020年5月于我院进行治疗的甲状腺机能亢进患者中选取84例,并以奇偶数法分为研究组和对照组,每组各42例,对照组患者使用丙基硫氧嘧啶治疗,研究组患者在此基础上联合使用抗甲协定方治疗,比较两组患者甲状腺功能、治疗有效率、不良反应发生率以及中医证候积分。结果:治疗前,两组患者甲状腺功能和中医证候积分没有明显差异(P>0.05);治疗后,研究患者甲状腺功能和中医证候积分明显优于对照组,且研究组患者治疗有效率更高而不良反应发生率更低(P<0.05)。结论:抗甲协定方与西药联合能够有效治疗甲状腺机能亢进,提升患者甲状腺功能、降低患者中医证候积分,且治疗安全性更高、不良反应发生率低,具有较高的应用价值。

Objective:To analyze and study the clinical effect of combined therapy of antithyroid and Western medicine in the treatment of hyperthyroidism.Methods:Using simple random sampling method,84 patients with hyperthyroidism who were treated in our hospital from May 2018 to May 2020 were divided into study group and Control Group by odd-even number method,the patients in the control group were treated with Propylthiouracil,and the patients in the study group were treated with antithyroid prescription.The thyroid function,the effective rate,the incidence of adverse reactions and the TCM syndrome scores were compared between the two groups.Results:Before treatment,there was no significant difference in thyroid function and Tcm Syndrome scores between the two groups(P>0.05),and after treatment,the patients'thyroid function and tcm syndrome scores were significantly better than those of the control group,the effective rate of treatment was higher and the incidence of adverse reactions was lower in the study group(P<0.05).Conclusion:The combination of anti-thyroid agreement and Western medicine can effectively treat hyperthyroidism,improve patients'thyroid function,reduce patients'Tcm Syndrome score,and have higher safety and lower incidence of adverse reactions,it has high application value.