胃溃疡患者应用奥美拉唑与阿莫西林治疗的效果及安全性分析

Effect and safety of omeprazole and amoxicillin in patients with gastric ulcer

目的:本文主要探究胃溃疡患者应用奥美拉唑与阿莫西林治疗的效果并分析其安全性。方法:将我院2018年5月至2020年5月内接收共90例胃溃疡患者分成参照组与研究组,参照组单独应用奥美拉唑药物治疗,研究组应用奥美拉唑与阿莫西林药物联合治疗,统计两组临床效果。结果:经统计,研究组治疗有效率高于参照组(P<0.05);研究组胃灼烧消退时间、反酸消退时间、溃疡愈合时间与HP根除时间均短于参照组(P<0.05);而在不良反应发生率上,研究组与参照组无明显差异(P>0.05)。结论:胃溃疡患者应用奥美拉唑与阿莫西林药物治疗的效果十分显著,安全性高。

Objective:This article mainly explores the efficacy and safety of omeprazole and amoxicillin in patients with gastric ulcer.Methods:From May 2018 to May 2020,90 patients with gastric ulcer received in our hospital were divided into reference group and study group.reference group was treated with omeprazole alone,and the study group was treated with omeprazole and amoxicillin.The clinical effects of the two groups were counted.Results:the effective rate of treatment in the study group was higher than that in the reference group(P<0.05);the time of gastric cauterization,regurgitation,ulcer healing and HP eradication in the study group were shorter than those in the reference group(P<0.05);however,there was no significant difference between the study group and the reference group in the incidence of adverse reactions(P<0.05).Conclusion:Omeprazole and amoxicillin are effective and safe in patients with gastric ulcer.