腹腔镜下穿孔修补术治疗胃穿孔的临床效果

Clinical effects of laparoscopic perforation repair for gastric perforation

目的探讨腹腔镜下穿孔修补术对胃穿孔患者胃肠功能及炎症因子水平的影响。方法选取2018年2月—2020年12月南阳市某医院收治的60例胃穿孔患者,采用随机数字表法分为对照组和实验组,每组30例。对照组患者采用传统开腹穿孔修补术治疗,实验组患者采用腹腔镜下穿孔修补术治疗,比较2组患者术后肠鸣音恢复时间、术后肛门排气时间、住院时间及术后炎症因子水平。结果实验组患者术后肠鸣音恢复时间、肛门排气时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。2组患者术前血清白介素-1β(IL-1β)、降钙素原(PCT)及白介素-10(IL-10)水平比较,差异无统计学意义(P>0.05);实验组患者术后血清IL-1β、PCT及IL-10水平均低于对照组,差异均有统计学意义(P<0.05)。结论腹腔镜下穿孔修补术治疗胃穿孔效果优于传统开腹修补术,有助于促进患者术后胃肠功能恢复,减轻术后炎症反应,值得临床推广使用。

Objective To investigate the effects of laparoscopic perforation repair on the gastrointestinal function and inflammatory factor levels in patients with gastric perforation.Methods Sixty patients with gastric perfora-tion admitted to a hospital in Nanyang from February 2018 to December 2020 were selected and divided into a control group and an experimental group using a random number table,with 30 cases in each group.Patients in the control group were treated with traditional open repair and patients in the experimental group were treated with laparoscopic perforation repair,and the recovery time of bowel sounds,time to first flatus,hospitalization time and postoperative inflammatory factor level were compared between the 2 groups.Results The recovery time of bowel sounds,time to first flatus and hospitalization time were all shorter in the experimental group than in the control group,and the differences were statistically significant(P<0.05).The differences between the preoperative serum interleukin-1β(IL-1β),procalcitonin(PCT)and interleukin-10(IL-10)levels in the two groups were not statistically significant(P>0.05);the postoperative serum IL-1β,PCT and IL-10 levels in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The effect of laparoscopic perforation repair for gastric perforation is better than that of traditional open repair,as it helps to promote the recovery of postoperative gastrointestinal function and reduce postoperative inflammatory reactions.Therefore,it is worthy of clinical promotion.