早发性结直肠癌的研究进展

Research progress of early-onset colorectal cancer

早发性结直肠癌(EO-CRC)近年来发病率持续上升,目前发病机制尚不清楚,其在流行病学、危险因素、临床特征等方面有别于结直肠癌,但治疗上往往采用结直肠癌的治法,临床缺少针对早发性结直肠癌的诊治方案。文章总结了早发性结直肠癌的流行病学特点、危险因素、临床特征、分子遗传学表征、治疗及预防策略,为临床早发性结直肠癌诊治提供理论依据。

The incidence rate of early-onset colorectal cancer(EO-CRC)has been increasing in recent years the pathogenesis is unclear.EO-CRC is different from colorectal cancer in terms of epidemiology,risk factors and clinical featuresthe treatment of EO-CRC is the same as that of colorectal cancer,is a lack of.This article summarized the epidemiological characteristics,risk factors,clinical features,molecular genetic characterization,treatment and prevention strategies of EO-CRC,in order to provide some inspiration for clinical treatment of EO-CRC.