摘要
睡眠障碍指机体受多种因素影响导致睡眠与觉醒机制异常,进而引发不同程度的睡眠相关疾病,其中最为常见的睡眠性疾病为失眠。酸枣仁是治疗焦虑与失眠的经典中草药之一,现代药理学研究表明皂苷、黄酮、生物碱与脂肪酸成分是酸枣仁发挥镇静催眠作用的主要生物活性成分。就酸枣仁中镇静催眠作用的有效活性成分及其机制进行综述。
Sleep disorder refers to the abnormal mechanism of sleep and wakefulness caused by many factors,and then leads to different degrees of sleep related diseases.The most common sleep disease is insomnia.Suanzaoren(Semen Ziziphi Spinosae)is one of the classic Chinese herbal medicines for treating anxiety and insomnia.Modern pharmacological studies have shown that saponins,flavonoids,alkaloids and fatty acids are the main biologically active constituents in Suanzaoren(Semen Ziziphi Spinosae),regulating sedative-hypnotic effect.This article reviewed the effective active components and their mechanism of sedative-hypnotic effect.
作者
李旭
和建政
陈彻
杨馥嘉
修明慧
LI Xu;HE Jianzheng;CHEN Che;YANG Fujia;XIU Minghui(School of Public Health,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China;School of Basic Medicine,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China)
出处
《中华中医药学刊》
CAS
北大核心
2022年第2期23-31,共9页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金青年科学基金(82004228)
甘肃省教育厅高等学校创新能力提升项目(2019A-071)。
关键词
酸枣仁
镇静催眠作用
皂苷
黄酮
生物碱
脂肪酸
Suanzaoren(Semen Ziziphi Spinosae)
sedative-hypnotic effect
saponins
flavonoids
alkaloids
fatty acids
