动脉瘤性蛛网膜下腔出血预后影响因素的研究进展

Research progress on prognostic factors of aneurysmal subarachnoid hemorrhage

动脉瘤性蛛网膜下腔出血(aSAH)是出血性卒中的常见亚型,具有较高的致死率、致残率。经过显微神经外科、介入外科和重症医学科等多学科数十年的发展,aSAH的存活率较前明显升高,但是大部分aSAH患者预后仍然较差,严重地影响了患者的生活质量。因此,探究aSAH预后影响因素成为了神经科医师的重点。自身因素、临床分级、动脉瘤的位置与数量、早期脑损伤(EBI)、贫血、炎症反应等均与aSAH的预后密切相关,对临床工作具有重要的指导意义。本文现将国内外对aSAH预后因素的研究进展进行综述。

Aneurysmal subarachnoid hemorrhage(aSAH) is a common subtype of hemorrhagic stroke,which has a high mortality and disability rate.After decades of development of microsurgery,interventional surgery and critical medicine,the survival rate of aSAH is significantly higher than before,but the prognosis of most aSAH patients is still poor,which seriously affects the quality of life of patients.Therefore,to explore the prognostic factors of aSAH has become the focus of neurologists.Self factors,clinical grade,location and number of aneurysms,early brain injury(EBI),anemia,inflammatory reaction are closely related to the prognosis of aSAH,which has important guiding significance for clinical work.This paper reviews the research progress on the prognostic factors of aSAH at home and abroad.