《卒中后失语患者报告结局量表》第1版第1轮临床验证

The first round of clinical verification of Patient Reported Outcomes Scale for Post-stroke Aphasia(the first draft)

目的:对《卒中后失语患者报告结局量表》第1版进行第1轮临床验证及优化。方法:课题组前期建立并优化条目池、编制形成了包括3个维度,40条条目的《卒中后失语患者报告结局量表》第1版。基于2019年3月—4月和2021年1月—2月收集的临床数据对该量表进行第1轮多中心临床验证,对量表进行可行性、区分度、信度、效度考评,参考考评结果进行优化。结果:量表整体完成率、接受率在90%以上,25条条目区分度具有统计学意义,分半信度系数为0.857,克朗巴赫系数为0.85,内容效度检测结果显示生理维度中6条与本维度的相关系数小于与其他维度的相关系数,余34条条目均大于与其他维度的相关系数。结合考评结果将第1版升为4个维度,删除12条条目,优化了《卒中后失语患者报告结局量表》。结论:《卒中后失语患者报告结局量表》第1版具有一定的可行性、敏感性、信度、内容效度,今后应结合专家意见,扩大样本量对量表进行进一步验证。

Objective: The first round of clinical verification was conducted on Patient Reported Outcomes Scale for Post-stroke Aphasia(the first draft), and its performance was investigated and revised. Methods: In the early stage, we had established and optimized the item pool, compiled and formed the Patient Reported Outcomes Scale for Post-stroke Aphasia(the first draft), which included 3 dimensions and 40 items. The first round of multi-center clinical verification was carried out on the basis of clinical data collected from March 2019 to April 2019 and January 2021 to February 2021. The feasibility, differentiation,reliability, and validity of the scale were evaluated, and the preliminary draft was revised according to the evaluation results.Results: The overall completion rate and acceptance rate of the scale were more than 90%. In the first draft, the degree of differentiation of 25 items was statistically significant, the dividing half reliability coefficient was 0.857 and the Kronbach coefficient was 0.85. The content validity test results show that the correlation coefficients of 6 of the physiological dimensions with this dimension were smaller than the correlation coefficients with other dimensions, and the remaining 34 items were all larger than the correlation coefficients with other dimensions. Combined with the evaluation results, the preliminary draft was upgraded to 4 dimensions, 12 items were deleted, and the Patient Reported Outcomes Scale for Post-stroke Aphasia was optimized. Conclusion:The Patient Reported Outcomes Scale for Post-stroke Aphasia(the first draft) has a certain degree of feasibility, sensitivity,reliability, and content validity. In the future, the scale should be further verified by combining expert opinions and expanding the sample size.