摘要
Optical coherence tomography(OCT)provides a non-invasive analysis of the retina in vivo.Lesions which compress the anterior visual pathway can cause anterograde and retrograde neuro-degeneration.Retrograde structural changes to the retina can be detected by OCT.Analyzing patterns of change on OCT can guide diagnostic and treatment decisions for lesions compressing the optic nerve and chiasm to minimize loss of visual function.From our review of current literature,it is clear that thinning of both the retinal nerve fiber and ganglion cell layers(GCLs)can indicate compression.These parameters correlate with visual function loss as detected by perimetry.Furthermore,these measurements have shown to be the most reliable biomarkers to date in predicting visual recovery after treatment of these compressive lesions.
