纳米碳示踪剂在cN0期甲状腺乳头状癌中央区淋巴结清扫术中的应用

Application of nano-carbon tracer in central lymph node dissection for cN0 papillary thyroid carcinoma

目的了解纳米碳示踪剂在cN0期甲状腺乳头状癌中央区淋巴结清扫术中应用效果。方法100例cN0期甲状腺乳头状癌患者随机分为观察组和对照组,两组均行甲状腺全切除及中央组淋巴结清扫,观察组加用纳米碳示踪剂。比较两组手术情况、淋巴结清扫和转移数、血钙和甲状旁腺激素(PTH)水平、并发症。结果观察组住院时间、术后2 d血钙和PTH水平、并发症低于对照组(P<0.01或0.05),而淋巴结清扫数和转移数多于对照组(P<0.01)。结论cN0期甲状腺乳头状癌中央区淋巴结清扫术中应用纳米碳示踪剂可提高淋巴结清扫效果,保护甲状旁腺功能。

Objective To study the application and efficacy of nano-carbon tracer in central lymph node dissection(CLND)for cN0 papillary thyroid carcinoma(PTC).Methods One hundred patients with cN0 PTC were randomly treated with total thyroidectomy and CLND with(observation group)or without(control group)nano-carbon tracer.Surgical conditions,number of lymph nodes removal and metastasis,blood calcium and parathyroid hormone(PTH)levels,and complications were compared between two groups.Results Compared with control group,hospital stay,blood calcium and PTH levels at postoperative day 2,and complications were lower(P<0.01-0.05),while number of lymph nodes removal and metastasis was higher(P<0.01)in observation group.Conclusion The application of nano-carbon tracer in CLND for cN0 PTC can enhance CLND efficiency and protect parathyroid function.