Posner-Schlossman syndrome:a 10-year review of clinical experience

Background:To describe our 10-year experience with Posner-Schlossman syndrome(PSS)in terms of morbidity and prognosis.Methods:We investigated 72 cases(74 eyes;both eyes of 2 cases)of PSS between July 2005 and July 2015.Data were collected on intraocular pressure(IOP),keratic precipitates(KP),anterior chamber,pupil,optic nerve disc and visual field,as well as general characteristics.Each case was examined every 3 to 7 days during attacks and every 2 to 6 months between attacks.Results:The mean age of the 72 patients(41 men)was 40±6 years(range,16-64 years).The mean disease duration was 4.3 years(range,1-7 years)and mean follow-up 4.9 years(range,1-8 years).Medical treatment was efficacious for 62 patients(62 eyes,83.78%).Ten patients exhibited progressive cupping and visual field loss(12 eyes,16.22%),all had normal IOP and no recurrence of PSS after trabeculectomy with anti-metabolite treatment.Conclusions:Although the prognosis of most PSS is usually benign,the IOP and optic nerve disc must be monitored.Visual-field damage can occur with long-term disease and frequent attacks.